Peripheral gangrene in a child as a result of Primary Thrombocytosis

Received: April 09, 2011
Accepted: August 21, 2011
Ref: Avasthi S, Tandon RK. Peripheral gangrene in a child as a result of Primary Thrombocytosis. Internet J Med Update. 2012 Jan;7(1):70-2.

PERIPHERAL GANGRENE IN A CHILD AS A RESULT OF PRIMARY THROMBOCYTOSIS

Shalini Avasthi* and R K Tandon** MD

*Assistant Professor, Department of Pediatrics, **Professor and Head, Department of Pediatric Surgery, Era Medical College, Lucknow, Uttar Pradesh, India

(Corresponding Author: Dr. Shalini Avasthi, Department of Pediatrics, Era Medical College, Lucknow, Uttar Pradesh, India; Email: drshalini79@rediffmail.com)

ABSTRACT

Essential Thrombocytosis (ET) is a clonal disorder of unknown etiology involving a multipotent hematopoietic progenitor cell and is manifested clinically by the overproduction of platelets without a definable cause. Clinically, ET is most often identified incidentally when a platelet count is obtained during the course of routine evaluation. There are very few case reports in the pediatric age group in which peripheral gangrene is caused by primary thrombocytosis or essential thrombocythemia. This is a case report of a 5 year old male child who presented to us as peripheral gangrene of toes which was caused by ET, one of the Myeloproloferrative disorders.

KEY WORDS: Essential thrombocythemia; Gangrene, Myeloproliferative disorder; Primary thrombocytosis

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