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Assessing Public Awareness of Symptoms of Acute Coronary Syndrome and Awareness of Cardiopulmonary Resuscitation
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Received: ,
Accepted: ,
How to cite this article: Moturu D, Rayana S, Kistipati H, Shaik M, Mallemudi G, Kanaparthi H, et al. Assessing Public Awareness of Symptoms of Acute Coronary Syndrome and Awareness of Cardiopulmonary Resuscitation. Glob J Med Pharm Biomed Update. 2026;21:06. doi: 10.25259/GJMPBU_64_2025
Abstract
Objectives:
Early recognition of symptoms and prompt hospital presentation for ischemic heart disease can significantly impact patient outcomes. Many patients delay treatment due to limited awareness of the symptoms of acute coronary syndrome (ACS). The study aimed to evaluate public awareness of ACS symptoms, risk factors, and the steps of cardiopulmonary resuscitation (CPR).
Material and Methods:
A cross-sectional questionnaire-based study was conducted in the outpatient department of a tertiary care hospital and a community clinic over 3 months. The questionnaire included details about demographics, education level, risk factors, typical symptoms, and information on how to respond to ACS initially. The questionnaire underwent expert review and pilot testing (n = 25). All the data were collected through one-on-one surveys with subjects aged 18–91.
Results:
A total of 801 subjects participated. Of these, 471 (58.8%) were male, and 330 (41.2%) were female. Of the participants, more than half (54.8%) knew that chest pain is a common symptom of ACS. A considerable proportion of the participants (74.9%) do not know how to perform CPR. More than two-fifths of subjects (44%) know that smoking increases the chance of ACS. Some respondents (74.1%) were unaware that diabetes mellitus patients do not experience symptoms of ACS.
Conclusion:
The study results revealed insufficient public awareness of ACS symptoms, risk factors, and CPR steps, particularly among females, younger adults, and non-graduates. We recommend targeted educational programs focusing on these vulnerable groups to improve early recognition and response, potentially reducing morbidity and mortality.
Keywords
Acute coronary syndrome
Awareness
Cardiopulmonary resuscitation
Mortality
Risk factors
INTRODUCTION
In 2020, around 523 million individuals were affected by cardiovascular disease (CVD), leading to approximately 19 million fatalities.[1] This figure increased to 20.5 million in 2021.[2] Ischemic heart disease (IHD) had the highest global age-standardized disability-adjusted life years rate of all diseases at 2,275.9/100,000.[3]
Preventing IHD involves controlling manageable risk factors such as diabetes mellitus, hypertension, increased cholesterol levels, obesity, and smoking.[4] Implementing effective population-based prevention programs could lead to a significant decrease in IHD-related illnesses and deaths.[5]
The extent of myocardium injury depends on the time taken to get appropriate treatment after the presentation of the symptoms.[6] Receiving prompt reperfusion within 1 hr can improve patient survival by up to 50%.[7] The failure to recognize the symptoms of acute coronary syndrome (ACS) is responsible for the delay in seeking treatment.[6] This delay occurs due to hesitancy to call for emergency help or seek medical care.[8-10] Early hospitalization is critical in reducing morbidity and mortality. Therefore, creating public awareness about IHD and its risk factors is essential.[11]
Both victims and bystanders must recognize the characteristics and symptoms of a heart attack and act promptly by contacting medical services.[12] According to the American Heart Association, Basic Life Support (BLS) can save approximately 50,000 lives yearly in the United States alone. However, this estimate is U.S.-specific and may not directly apply globally or to the Indian context,[13] where rates of public awareness and bystander cardiopulmonary resuscitation (CPR) remain significantly lower. CVDs pose a significant health burden worldwide and in India, it is important to emphasize the urgent need for increased public knowledge and motivation to perform BLS effectively before professional help arrives.[13-16]
The primary objective was to assess the level of public awareness regarding the symptoms and risk factors of ACS among adults in outpatient and community settings. The secondary objective was to determine the public understanding of the recommended initial response to ACS, including CPR steps, in the same adult population.
MATERIAL AND METHODS
Study design and study duration
A cross-sectional study was carried out for 3 months. Data were collected using a pre-designed questionnaire. The study got approved by the Institutional Ethics Committee.
Study tools
The questionnaire was prepared for the present research and covers demographic information, educational levels, and risk factors associated with ACS (smoking, alcohol consumption, hypertension, obesity, diabetes, stress, and physical inactivity). It also includes common ACS symptoms such as chest pain, shortness of breath, neck pain, left arm/shoulder pain, dizziness, fatigue, palpitations, sweating, and anxiety. In addition, it examines the initial response to ACS, including seeking immediate medical assistance, self-medication, or other actions. The questionnaire was available in both the local and English languages.
Questionnaire validation
The questionnaire was validated through an expert review involving five cardiology specialists and two public health specialists, who assessed its content relevance and clarity. Based on their feedback, medical terms were simplified into layperson–friendly language, redundant items on symptom recognition were merged, and ambiguous response options were refined for clarity. Subsequently, a pilot test was conducted on 25 participants to assess feasibility and internal consistency, yielding a Cronbach’s alpha of 0.78. The finalized version of the questionnaire is provided as a supplementary file.
Sample size and study site
The present study was conducted in a cardiology outpatient department (OPD) at a tertiary care hospital and a community clinic in South India. A systematic random sampling method was used. Every 4th visitor was involved, resulting in the 801 subjects included in the study.
Study criteria
Adults aged >18 years who are willing to participate and able to provide informed consent in the cardiology OPD and community clinic were included in the study. Those who have language barriers, patients aged under 18 years, inpatients, patients from other departments, and patients with severe illness were excluded from the study.
Age-group categorization
Age groups were categorized unevenly based on local demographics and participant distribution, with 18-year-olds segregated to capture initial adult awareness distinctly from the broader younger adult group of 19–34 years.
Statistical analysis
The method used for collecting information involved using predetermined Google Forms and the subsequent recording of responses in spreadsheet format. A thorough error check was done. The data were imported into the IBM Statistical Package for the Social Sciences Statistics, Version 29. Descriptive statistics were used to analyze the demographic variables and response distributions, with categorical variables presented as frequencies and percentages.
Inferential statistical analysis was conducted to examine associations between demographic variables (such as age, gender, and educational status) and awareness levels related to ACS, its symptoms, risk factors, and CPR procedures. The Chi-square test was used to assess associations between categorical variables. P < 0.05 was considered statistically significant. All analyses were two-tailed.
RESULTS
Demographic characteristics
In the present study, 801 individuals participated. Among them, 471 (58.8%) were male, and 330 (41.2%) were female. The oldest participant was 91 years old, while the youngest was 18. The participants were grouped into various groups: 6 (0.74%) were 18 years, 48 (5.9%) were between 19 and 34 years, 177 (22.09%) were between 35 and 49 years, 346 (43.19%) were between 50 and 64 years, 212 (26.4%) were between 65 and 79 years, and 12 (1.4%) were above 80 years old. About 32.4% of the participants had a graduate level of education, while 67.6% were non-graduates.
Awareness and response patterns regarding ACS
Awareness of ACS among both genders is shown in Table 1. The findings of the present study showed that those aged 50–64 and 65–79 displayed heightened awareness of symptoms and CPR procedures compared to younger cohorts (P < 0.001) [Table 2]. In addition, graduates exhibited a higher level of understanding regarding ACS (33.6%) than non-graduates (21.7%, P = 0.001).
| Item | Female n (%) | Male n (%) | Total (n=801) | P-value |
|---|---|---|---|---|
| 1. Do you know what acute coronary syndrome is? | 191 (35.4) | 349 (64.6) | 540 (67.4) | 0.001* |
| 2. Do you know that diabetic patients do not have symptoms of acute coronary syndrome? | 78 (37.7) | 129 (62.3) | 207 (25.8) | 0.33* |
| 3. What is the first thing you do when a person next to you develops symptoms of acute coronary syndrome? | ||||
| a. See the nearest doctor | 162 (36.1) | 287 (63.9) | 449 (56.05) | 0.01* |
| b. Self-medicate and treat, wait for some time, and go to the doctor | 18 (24.3) | 56 (75.7) | 74 (9.2%) | 0.01* |
| c. Don’t know what to do | 150 (54.2) | 128 (46) | 278 (34.7) | 0.01* |
| 4. Do you know what CPR is? | 242 (44.7) | 299 (55.3) | 541 (67.5) | 0.23 |
| 5. What are the initial steps of CPR? | 74 (36.8) | 127 (63.2) | 201 (25.09) | 0.001* |
| 6. Recognized >5 risk factors of ACS | 93 (36.8) | 159 (63.2) | 252 (31.4) | 0.001* |
| 7. Recognized >5 symptoms of ACS | 110 (33.3) | 220 (66.7) | 330 (41.2) | 0.002* |
| Age group (years) | Do you know what acute coronary syndrome is? | Do you know that diabetic patients do not have symptoms of acute coronary syndrome? | What is the first thing you do when a person next to you develops symptoms of acute coronary syndrome? (See the nearest doctor) | Do you know what CPR is? | What are the initial steps of CPR? | P-value |
|---|---|---|---|---|---|---|
| 18 | 6 (1.1) | 0 (0.0) | 4 (0.9) | 7 (1.3) | 0 (0.0) | 0.001* |
| 19–34 | 40 (7.4) | 26 (12.6) | 33 (7.3) | 14 (2.6) | 30 (14.9) | |
| 35–49 | 136 (25.2) | 64 (30.9%) | 117 (26.1) | 97 (17.9) | 64 (31.8) | |
| 50–64 | 225 (41.7) | 75 (36.2) | 198 (44.1) | 247 (45.7) | 65 (32.3) | |
| 65–79 | 126 (23.3) | 42 (20.3) | 93 (20.7) | 165 (30.5) | 40 (19.9) | |
| >80 | 7 (1.3) | 0 (0.0) | 4 (0.9) | 11 (2.0) | 2 (1.0) |
All age groups had *P<0.001 by Chi-square test. CPR: Cardiopulmonary resuscitation
Awareness of ACS symptoms among the study participants
Individuals aged 50–64 showed higher awareness levels, with 38.9% recognizing more than five symptoms. Graduates demonstrated better awareness, with 63.0% recognizing over five symptoms compared to 37.0% of the non-graduates (P = 0.001). The most recognized symptom was chest pain (54.8%), followed by pain in the left arm or shoulder (42.9%), neck pain (29%), shortness of breath (25.9%), dizziness (23.6%), sweating (22.8%), palpitations (16%), and anxiety (14.6%). Fatigue was the least identified symptom (13.5%) [Figure 1]. In addition, 33.1% of participants were unaware of any ACS symptoms.

- Awareness of symptoms of acute coronary syndrome among the study participants.
Awareness of ACS risk factors across demographics
In the present research study, gender variations were found in the awareness of ACS risk factors. Out of the seven ACS risk factors mentioned in our questionnaire, 63.2% of males recognized more than five risk factors, while only 36.8% of females did so (P = 0.001). Age also played a role, with 45.6% of individuals aged 50–64 recognizing more than five risk factors. Education was also a significant factor, as graduates recognized >5 risk factors compared to non-graduates (P = 0.001) [Table 3]. These findings emphasize the necessity for organized educational campaigns to improve awareness, particularly among females, younger individuals, and those with lower educational attainment. Notably, 44% of subjects knew that smoking is a risk factor for ACS, followed by alcohol (42.3%), obesity (36.8%), high blood pressure (32.1%), and stress (22.5%). However, diabetes mellitus (18.6%) and inadequate physical activity (13.4%) were the least recognized risk factors. In addition, 40.8% of the respondents did not identify at least one risk factor for ACS.
| Recognized more than five risk factors of ACS | Graduate n (%) | Non-graduate n (%) | Total (n=801) | P-value |
|---|---|---|---|---|
| Recognized ≥5 risk factors | 166 (63.8) | 94 (36.2) | 260 (32.5) | 0.001* |
| Recognized <5 risk factors or none | 94 (36.2) | 447 (82.6) | 541 (67.5) |
A significant proportion of respondents (74.1%) were unaware that diabetes mellitus patients do not have typical ACS symptoms. Overall, 539 (67.4%) respondents in our study knew about ACS and its consequences.
DISCUSSION
Delayed reporting to medical facilities after the onset of ACS symptoms continues to be a serious global issue that increases the morbidity and mortality rates.[8] In our study, a third of subjects were unaware of ACS symptoms, which is consistant with the United States and South Korean studies.[17,18] Chest pain was the most recognized symptom, mirroring results from multiple Asian studies.[10,17] However, Dizziness, sweating, palpitations, anxiety, and fatigue were the least recognized symptoms in the present study, as observed in the studies conducted across the world.[12,19-21]
Male participants exhibited a greater awareness of heart attack symptoms than females in the present research. Conversely, Kim et al., and Khan et al., research revealed that females had higher knowledge of myocardial infarction symptoms than males.[22-23] Despite this, it suggests a gender gap in health education, necessitating targeted interventions to improve awareness and response to ACS symptoms. The gender gap observed in our study may reflect cultural and societal factors in India, where men generally have greater exposure to health information through employment, social mobility, and healthcare interactions, whereas women often have limited access to preventive health education due to domestic roles and lower participation in community programs. Similar disparities in cardiovascular health awareness among Indian women have been highlighted by Prabhakaran et al.[24] These findings underscore the need for gender-sensitive educational interventions to improve women’s cardiovascular health literacy.
There is a significant connection between education and understanding of ACS. Graduates demonstrated higher levels of knowledge in recognizing more than five ACS risk factors and symptoms than non-graduates in the present study. These findings demonstrate that higher education improves health literacy. These results suggest that health awareness programs should target less educated individuals through community programs and simplified health messages.
The participant’s awareness of ACS risk factors varied. Smoking was the most recognized risk factor, followed closely by alcohol consumption, overweight, hypertension, and stress, consistent with the Ahmed et al., and Mohammad et al., study results.[20,25,26] However, diabetes mellitus and inadequate exercise were poorly identified. Mirroring the results from research studies in Ethiopia and Oman, and Khan et al. and Ahmed et al.[20,23,27-30].In Contrast, Ramachandran et al.’s study, around two-thirds of the participants, identified diabetes as a risk factor for coronary heart disease.[31] Many campaigns have been conducted on quitting smoking.[30] The above results insist that thorough educational training is required to address a wide range of ACS risk factors, including less recognized ones such as diabetes and physical inactivity.
The current results revealed that males are more aware of ACS risk factors than females. In contrast, women had more awareness than men in research in Buea.[32] This indicates that public health campaigns should adopt gender-specific strategies to better educate men and women about ACS risk factors.
In the present study, more than half of the participants said that they would take the person having ACS symptoms to consult the nearest doctor, which is consistent with the Nepalese study.[33] Conversely, the first response to ACS symptoms was low in the study conducted in Turkey.[34] Abdo Ahmed et al. noted that public knowledge of ACS first responses is lower in developing countries than in developed ones.[8] These findings highlight a significant delay in initial responses to ACS, stressing the need for better public education.
Cardiac arrest is a medical emergency where early CPR can significantly improve survival and reduce neurological damage. Despite the critical role of the CPR, global public knowledge and behavior regarding CPR are often lacking. In our study, only a third of participants were aware of CPR. Furthermore, a quarter of the subjects knew the initial steps of CPR, which aligns with the results of the Varleta et al., study.[35] Among the present research participants, older age groups (50–64 and 65–79) showed higher CPR awareness than younger groups. Contrary to this, a study in Austria by Krammel et al. found decreasing CPR knowledge and willingness to perform it with increasing age.[32] Research carried out by Agarwal et al. in northern India revealed that the baseline knowledge level of CPR among physicians and nurses has considerably improved after resuscitation training was introduced.[36] A similar study was conducted by Saramma et al, in South India, which showed that there was significant improvement in their knowledge, skill, and attitude. A further half of the patients agreed that it improved their communication, while above two-thirds of participants confirmed that it increased their confidence after CPR training.[29] The observed low CPR awareness aligns with global and Indian data, highlighting limited public training and readiness. Recent initiatives, such as Pan-India CPR Awareness Week in 2025, underscore the importance of building a culture of resuscitation literacy. To strengthen CPR preparedness, structured interventions should include integrating BLS and CPR education into school and college curricula, community-based programs and workplace initiatives to improve public knowledge, confidence, and willingness to respond effectively during cardiac emergencies.
The study findings show poor awareness of CPR skills among the public and even those with previous heart disease. Critical care physicians need to make a nationwide effort to improve public awareness of CPR.
Limitations
The inclusion of participants from a cardiology OPD may have introduced selection bias, as these individuals could possess higher baseline awareness of cardiovascular conditions due to prior exposure to medical advice and educational materials. A fully community-based survey was not conducted due to resource constraints; however, combining cardiology OPD and general clinic participants provided a modest representation of public awareness.
The use of self-reported data may have introduced response bias, as participants could overestimate or underestimate their knowledge and awareness levels. Furthermore, the cross-sectional design limits causal inference, as associations observed cannot establish cause-and-effect relationships
We did not do construct validity in the present study, this is acknowledged as beyond the present scope. We suggest that future research studies validate this instrument experimentally.
CONCLUSION
The study results revealed insufficient public awareness of ACS symptoms, risk factors, and CPR steps, particularly among females, younger adults, and non-graduates. We recommend targeted educational programs focusing on these vulnerable groups to improve early recognition and response, potentially reducing morbidity and mortality.
Acknowledgment:
We thank all co-authors for their assistance and support in conducting this study.
Ethical approval:
The research/study approved by the Institutional Ethics Committee at Dr. Ramesh Cardiac and Multispeciality Hospital P Ltd., number ECRH052024, dated 23rd March, 2024.
Declaration of patient consent:
The authors certify that they have obtained all appropriate patient consent forms. In the form, the patients have given their consent for their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Conflicts of interest:
There are no conflicts of interest.
Use of artificial intelligence (AI)-assisted technology for manuscript preparation:
The authors confirm that there was no use of artificial intelligence (AI)-assisted technology to assist in the writing or editing of the manuscript and no images were manipulated using AI.
Financial support and sponsorship: Nil.
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